Understanding Inflammation
and How Renadyl® Helps

What Is Inflammation in Chronic Kidney Disease (CKD)?

Inflammation is your body’s natural way of protecting itself from injury or infection. But in CKD, inflammation can become long-lasting and harmful, quietly damaging your kidneys and contributing to complications like heart problems, fatigue, and faster kidney decline.

While short-term inflammation helps you heal, chronic inflammation in CKD can put extra stress on your kidneys and your overall health.

Understanding Inflammation and Kidney Health

Talk to your doctor about how chronic inflammation plays a major role in CKD. Doctors can measure inflammation using specific blood tests that show how active it is in your body:

  • C-reactive protein (CRP): A protein that increases when your body is inflamed. High CRP levels can signal kidney stress and raise heart disease risk.
  • Other markers like IL-6 and TNF-alpha: These are chemicals that indicate inflammation and may contribute to kidney damage over time.

At the same time, when kidneys don’t filter as efficiently, as in Chronic Kidney Disease, certain waste compounds from the gut can build up in the blood and fuel more inflammation:

  • p-Cresol sulfate (PCS): Produced by gut bacteria when breaking down protein; high levels can harm kidneys and blood vessels.
  • Indoxyl sulfate (IS): Another gut-derived toxin that can contribute to both kidney and heart stress.

Together, these inflammatory markers and gut-derived toxins can create a cycle that further damages the kidneys and affects overall health.

Renadyl icon, colon-gut-health
Renadyl icon, colon-gut-health

The Gut-Kidney Connection: How the Gut Affects Kidney Health and Inflammation

The gut and kidneys communicate closely, and inflammation in the gut can influence how hard the kidneys need to work.

  • Your gut helps regulate immune signals and toxins that affect inflammation throughout the body.
  • When the gut is healthy, fewer inflammatory compounds like p-cresol sulfate (PCS) and indoxyl sulfate (IS) enter the bloodstream, which helps reduce stress on the kidneys.
  • When the gut becomes irritated or disrupted, more inflammatory substances can circulate and contribute to kidney strain.

The good news? Supporting gut health with Renadyl helps protect kidney function and can lower inflammation markers such as CRP. By keeping your gut in balance, you support your body’s natural ability to manage inflammation and maintain long-term kidney health.

Renadyl Helps Reduce Inflammation

Renadyl is a probiotic supplement designed to maintain healthy kidney function and strengthen gut health. It contains proprietary strains of good bacteria — Streptococcus thermophilus, Lactobacillus acidophilus, and Bifidobacterium longum — that help reduce toxins and inflammation.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Here’s How Renadyl Helps:

  1. Reduces Harmful Toxins and CRP Renadyl helps metabolize p-cresol sulfate, indoxyl sulfate, and other waste products in your gut. This can lower CRP levels and reduce the inflammation that stresses your kidneys.
  2. Supports Anti-Inflammatory Compounds Friendly gut bacteria help produce short-chain fatty acids (SCFAs), which are natural compounds that calm inflammation in the body.
  3. Supports a Healthier Digestive Balance The probiotics in Renadyl help beneficial bacteria thrive while limiting those that drive inflammation.

Concerned About Inflammation and CKD?

Talk to your doctor about taking one Renadyl capsule twice a day consistently for at least six months. Combine with good hydration and a kidney-friendly diet for best results.

Backed by Research

Studies show that probiotics like Renadyl can:

  • Lower CRP and other inflammation markers
  • Reduce pro-inflammatory toxins from the gut
  • Support healthier BUN, creatinine, uric acid, and eGFR levels
  • Improve energy, digestion, and overall wellness for people with CKD

Learn more about gut health and CKD on NIH.gov

Tips to Reduce Inflammation Naturally

  • Eat a kidney-friendly diet rich in fruits, vegetables, and anti-inflammatory foods
  • Take Renadyl to help reduce harmful gut toxins
  • Stay active with doctor-approved exercise
  • Get good sleep and manage stress
  • Avoid smoking, excess alcohol, and processed foods

Stay Informed About Kidney Health and Gut Science.

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FAQs About Inflammation and Renadyl

Can probiotics really help with inflammation in CKD?

Yes. Renadyl helps your gut process toxins that trigger inflammation, which can lower CRP and protect your kidneys.

Yes, it’s generally safe. Always check with your healthcare provider before starting any supplement.

No. Renadyl is a supplement that works alongside your doctor’s treatments, diet, and lifestyle changes.

Most users tolerate probiotics well. Mild digestive changes may occur at first; contact your doctor if you have concerns.

Learn More About Other Key Kidney Function Markers Here

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These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.